The Amazing Screw-On Head

Paul Giamatti

Screw-On Head (voice)

David Hyde Pierce

Emperor Zombie (voice)

Patton Oswalt

Mr. Groin (voice)

Corey Burton

President Abraham Lincoln / Demon / Professor Faust (voice)

Mindy Sterling

Aggie / Geraldine (voice)

Molly Shannon

Patience the Vampire (voice)